Infants who are born before 37 weeks of gestation and have birth weight less than 2.5 Kg are termed as Preterm Low-Birth Weight Neonates. It is vital to analyze the distribution of characteristics of Preterm Low-Birth Weight Neonates such as age at admission, sex, birth weight, gestational duration and nutritional approaches for meeting their needs of specialized care. The study aims to explore uniformity in Clinical Profile of these neonates. A cross-sectional study investigation was carried out among 122 neonates at a tertiary level NICU from July 2024 to December 2024 using consecutive sampling technique. Data was gathered on age, sex, birth weight, gestational age, and feeding practices using Case Record Form. The chi-square test was used to analyze the findings. It revealed thattheir birth weights point outneed for advanced NICU resources, and their diverse traits make them an ideal group for learning more about preterm care.